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Aberrant expression of the testis kinase TSSK6activates FAK–STAT3 signaling to promote tumorigenic growth

2026-03-13

Abstract excerpt

Cancer–testis antigens (CTAs) are germ cell–restricted proteins aberrantly expressed in diverse malignancies, yet whether these proteins contribute to tumor progression remains poorly defined. The CTA Testis-Specific Serine Kinase 6 (TSSK6) is frequently expressed in colorectal cancer (CRC), where it promotes key hallmarks of tumor progression, including anchorage-independent growth, invasion, and in vivo tumor fo...

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Literature Corpus work
b4bbbc91-e7a8-51eb-abcc-07c8f85995cb
DOI
10.64898/2026.03.10.710807
Open publication

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Aberrant expression of the testis kinase TSSK6activates FAK–STAT3 signaling to promote tumorigenic growthDOI 10.64898/2026.03.10.710807
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