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Article

ETS1 induction by the microenvironment promotes ovarian cancer metastasis through focal adhesion kinase

23 Nov 2017

Abstract excerpt

Metastatic colonization involves paracrine/juxtacrine interactions with the microenvironment inducing an adaptive response through transcriptional regulation. However, the identities of transcription factors (TFs) induced by the metastatic microenvironment in ovarian cancer (OC) and their mechanism of action is poorly understood. Using an organotypic 3D culture model recapitulating the early events of metastasis,...

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PMID: 29174800
DOI: 10.1016/j.canlet.2017.11.012

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