Article
OMICs based identification of the mechanisms that underpin FAK's regulation of gene expression
2020-01-01
Abstract excerpt
Focal adhesion kinase (FAK) is a non-receptor tyrosine kinase, commonly overexpressed in cancer that is well known to be a key regulator of cancer cell proliferation, survival, migration and invasion. It has recently been shown to modulate the antitumour immune response via transcriptional regulation of chemokines and cytokines. These findings have fuelled interest in FAK as a plausible therapeutic target in cance...
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- 24c91cd0-8180-5ca3-85db-18100656c88c
- DOI
- 10.7488/era/161