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Article

Contradictory Effects of NLRP3 Inflammasome Regulatory Mechanisms in Colitis

30 Oct 2020

Abstract excerpt

The inflammasome is an intracellular molecular complex, which is mainly involved in innate immunity. Inflammasomes are formed in response to danger signals, associated with infection and injury, and mainly regulate the secretion of interleukin-1β and interleukin-18. Inflammasome dysregulation is known to be associated with various diseases and conditions, and its regulatory mechanisms have become of great...

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PMID: 33143375
DOI: 10.3390/ijms21218145

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