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Gastrointestinal microbiota and inflammasomes interplay in health and disease: a gut feeling

28 May 2025

Abstract excerpt

The intricate interplay between the gut microbiota and the GI tract has garnered significant attention, as growing evidence has identified the inflammasome as a crucial yet underexplored master regulator in microbiota-driven diseases. Triggered by a variety of dangers, inflammasomes are supramolecular complexes that regulate immune response. A large number of bacterial-derived inducers have been characterised so...

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PMID: 40441864
DOI: 10.1136/gutjnl-2025-334938

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