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Article

The Multifaceted Role of the Inflammasome in Inflammatory Bowel Diseases

1 Jan 2011

Abstract excerpt

Inflammasomes are intracellular multiprotein complexes that coordinate the maturation of interleukin (IL)-1 beta and IL-18 in response to pathogens and metabolic danger. Both cytokines have been linked to intestinal inflammation. However, recently evolving concepts ascribe a major role to the inflammasome in maintaining intestinal homeostasis. This review recapitulates its position in the development of...

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Share to Congenital gastrointestinal and neural anomalies
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PMID: 21805022
DOI: 10.1100/tsw.2011.139

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