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Axonal mRNA transport and translation at a glance

13 Apr 2018

Abstract excerpt

Localization and translation of mRNAs within different subcellular domains provides an important mechanism to spatially and temporally introduce new proteins in polarized cells. Neurons make use of this localized protein synthesis during initial growth, regeneration and functional maintenance of their axons. Although the first evidence for protein synthesis in axons dates back to 1960s, improved methodologies,...

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PMID: 29654160
DOI: 10.1242/jcs.196808

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