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Article

LINE-1 retrotransposon activation intrinsic to interneuron development

2022-03-20

Abstract excerpt

Retrotransposons are a reservoir of cis-regulatory innovation 1–3 . Developmental programs that activate these elements could, in principle, manifest in lineage-specific retrotransposition. Somatic LINE-1 (L1) retrotransposon insertions have been detected in human and non-human primate neurons 4–7 . It is however unknown whether L1 is mobile in only some neuronal lineages, or therein regulates neurodevelopmental...

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Literature Corpus work
b4395ea2-4e5e-5787-87e3-11e2bd15cb9b
DOI
10.1101/2022.03.20.485017
Open publication

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LINE-1 retrotransposon activation intrinsic to interneuron developmentDOI 10.1101/2022.03.20.485017
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