Article

Pro-Inflammatory Molecules Implicated in Multiple Sclerosis Divert the Development of Human Oligodendrocyte Lineage Cells

2024-12-17

Abstract excerpt

<h4>Background and Objectives</h4> Oligodendrocytes (OL) and their myelin-forming processes are targeted and lost during the disease course of Multiple Sclerosis (MS), targeted by infiltrating leukocytes and their effector cytokines. Myelin repair is considered to be dependent on recruitment and differentiation of oligodendrocyte precursor cells (OPCs). The basis of failure of re-myelination during the disease co...

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Literature Corpus work: b423458d-3d33-5047-91a2-2c7bc6370956
DOI: 10.1101/2024.12.17.628958

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