Article

The role of the PWWP domain in the DNA methyltransferase 3A targeting to the genome

2021-01-01

Abstract excerpt

All cells in a mammalian body share the same DNA content but have a distinct appearance and function. This is achieved by activation and repression of genes by epigenetic mechanisms, which are crucial for stable differentiation of cells in a multi-cellular organism. DNA methylation, established by DNA methyltransferase (DNMT) enzymes, regulates gene expression and is essential for mammalian development. Histone ta...

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Literature Corpus work: b3cbd66d-bab8-5142-b24d-9b0fac6c5291
DOI: 10.17863/cam.71375

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