Article

Applying polygenic risk scoring for psychiatric disorders to a large family with Bipolar Disorder and Major Depressive Disorder

2017-01-27

Abstract excerpt

<h4>ABSTRACT</h4> We aim to investigate the application of polygenic risk scoring within a family context. Polygenic risk profiles could aid in unraveling the role that common variation confers on disease risk within a pedigree that would have traditionally been viewed through the prism of monogenic inheritance only. We illustrate our discussion by analyzing polygenic risk scores for schizophrenia, major depressi...

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Literature Corpus work: b3272574-e8f0-5d59-9173-d27703284730
DOI: 10.1101/103713

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