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Polygenic Risk Scores for Bipolar Disorder: Progress and Perspectives

1 Nov 2023

Abstract excerpt

Bipolar disorder (BD) is a common and highly heritable psychiatric disorder, the study of BD genetic characteristics can help with early prevention and individualized treatment. At the same time, BD is a highly heterogeneous polygenic genetic disorder with significant genetic overlap with other psychiatric disorders. In recent years, polygenic risk scores (PRS) derived from genome-wide association studies (GWAS)...

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PMID: 38050614
DOI: 10.2147/ndt.s433023

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