Article

Potential use of clinical polygenic risk scores in psychiatry – ethical implications and communicating high polygenic risk

2018-11-28

Abstract excerpt

Psychiatric disorders present distinct clinical challenges which are partly attributable to their multifactorial aetiology and the absence of laboratory tests that can be used to confirm diagnosis or predict risk. Psychiatric disorders are highly heritable, but also polygenic, with genetic risk conferred by interactions between thousands of variants of small effect that can be summarized in a polygenic risk score....

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Literature Corpus work: 32d7d436-099f-567a-86e0-94e2fc715c9b
DOI: 10.7287/peerj.preprints.27392v1

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