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Antimicrobial peptides do not directly contribute to aging in <i>Drosophila</i> , but improve lifespan by preventing dysbiosis

2022-08-25

Abstract excerpt

Antimicrobial peptides (AMPs) are innate immune effectors first studied for their role in host defense against bacterial and fungal infections. Recent studies have implicated these peptides in the clearance of aberrant cells and various neurological processes including neurodegenerative syndromes. In Drosophila , an array of AMPs are produced downstream of the Toll and Imd NF-κB pathways in response to infection....

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Literature Corpus work
b322f99a-a76e-59dc-91e8-0618005ab38a
DOI
10.1101/2022.08.24.504952
Open publication

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Antimicrobial peptides do not directly contribute to aging in <i>Drosophila</i> , but improve lifespan by preventing dysbiosisDOI 10.1101/2022.08.24.504952
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