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Article

Anti-tumor effects of antimicrobial peptides, targets of the innate immune system, against hematopoietic tumors in <i>Drosophila mxc</i> mutants

2018-10-25

Abstract excerpt

The innate immune response is the first line of defense against microbial infections. In Drosophila , three immune pathways induce the synthesis of antimicrobial peptides (AMPs) in the fat body. Recently, it has been reported that certain cationic AMPs exhibit selective cytotoxicity against human cancer cells. However, little is known about their anti-tumor effects. Drosophila mxc mbn1 mutants exhibit malignant...

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Literature Corpus work
ff8eb592-c1e0-5260-9f25-1fee300118a1
DOI
10.1101/452961
Open publication

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