Back to search

Article

Leveraging <i>Drosophila</i> Models to Explore AI-generated Synthetic Peptide’s Potential in Boosting Honeybee Health and Resilience

2024-12-25

Abstract excerpt

<h4>ABSTRACT</h4> The integration of artificial intelligence (AI) and machine learning (ML) in peptide design has revolutionized the development of antimicrobial peptides (AMPs), which are essential components of innate immunity. In this study, we identified a novel synthetic peptide, PAN4 (GAYTFKIRRK), through genetic screening of AI-generated candidates in Drosophila melanogaster . PAN4 demonstrated robust ant...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
25ec008e-55b2-5d63-90fc-641a205144dd
DOI
10.1101/2024.12.24.630224
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Leveraging <i>Drosophila</i> Models to Explore AI-generated Synthetic Peptide’s Potential in Boosting Honeybee Health and ResilienceDOI 10.1101/2024.12.24.630224
Membrane Tethering of Honeybee Antimicrobial Peptides in <i>Drosophila</i> Enhances Pathogen Defense at the Cost of Stress-Induced Host VulnerabilitySemantic proximity
Innovative Strategies and Methodologies in Antimicrobial Peptide DesignSemantic proximity
Antimicrobial peptides do not directly contribute to aging in <i>Drosophila</i> , but improve lifespan by preventing dysbiosisSemantic proximity
Anti-tumor effects of antimicrobial peptides, targets of the innate immune system, against hematopoietic tumors in <i>Drosophila mxc</i> mutantsSemantic proximity
<i>Drosophila</i> antimicrobial peptides and lysozymes regulate gut microbiota composition and abundanceSemantic proximity
Anti-Tumor Effects of Cecropin A and Drosocin Incorporated into Macrophage-Like Cells Against Hematopoietic Tumors in <i>Drosophila mxc</i> MutantsSemantic proximity
A humoral stress response protects <i>Drosophila</i> tissues from antimicrobial peptidesSemantic proximity
Efficacy and safety evaluation of artificial intelligence-identified antimicrobial peptides for use against avian pathogenic <i>Escherichia coli</i> in the poultry industrySemantic proximity
New potential antimicrobial peptides with amazing symmetrical structure in fungi and insectsSemantic proximity
Genome wide identification of Plant based natural Antimicrobial Peptides using deep learning approach in Black pepperSemantic proximity
Comprehensive Biosynthetic Analysis of Human Microbiome Reveals Diverse Protective Ribosomal PeptidesSemantic proximity
A PLUM Job: Peptide modeLs for Understanding and engineering antiMicrobial therapeuticsSemantic proximity
Select a neighboring publication to make it the new centre.