Article

Role of ADMA-histones in dual-strand piRNA source loci recognition by Rhino

2024-03-15

Abstract excerpt

In Drosophila germ cells, piRNAs arise from dual-strand piRNA clusters, which are marked by a repressive histone mark H3K9me3, but are transcribed from internal sites in a manner dependent on the HP1 homolog Rhino. Rhino binds to H3K9me3 on these clusters, yet the mechanism controlling its binding to clusters remains unclear. Here, we used cultured ovarian somatic cells (OSCs), which lack endogenous Rhino and its...

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Literature Corpus work: b311bbe3-1d1d-572f-a6c3-ae14ee107bde
DOI: 10.1101/2024.03.15.585151

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