Article

The Drosophila OSC Genome: A Resource for Studies of Transposon and piRNA Biology

2025-10-10

Abstract excerpt

<h4>ABSTRACT</h4> Accurate genome assemblies are critical for understanding small RNA-mediated genome defense. In animals, the PIWI-interacting RNA (piRNA) pathway protects genome integrity by silencing transposable elements. Studying how piRNAs are generated and how they guide heterochromatin formation requires complete reconstruction of genomic piRNA source loci and detailed transposon maps. Here, we present a...

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Literature Corpus work: abc0a9c7-c990-5d23-b33a-6c8a255ab071
DOI: 10.1101/2025.10.09.681131

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