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Article

Extrachromosomal circular DNA is common in yeast.

Proceedings of the National Academy of Sciences of the United States of America - 16 Jun 2015

Møller Henrik D, Parsons Lance, Jørgensen Tue S, Botstein David, Regenberg Birgitte

Abstract excerpt

Examples of extrachromosomal circular DNAs (eccDNAs) are found in many organisms, but their impact on genetic variation at the genome scale has not been investigated. We mapped 1,756 eccDNAs in the Saccharomyces cerevisiae genome using Circle-Seq, a highly sensitive eccDNA purification method. Yeast eccDNAs ranged from an arbitrary lower limit of 1 kb up to 38 kb and covered 23% of the genome, representing...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 26038577
DOI: 10.1073/pnas.1508825112
PMCID: PMC4475933

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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