Article
Chromosome-level genome of Schistosoma haematobium underpins genome-wide explorations of molecular variation.
PLoS pathogens - 1 Feb 2022
Stroehlein Andreas J, Korhonen Pasi K, Lee V Vern, Ralph Stuart A, Mentink-Kane Margaret, You Hong, McManus Donald P, Tchuenté Louis-Albert Tchuem, Stothard J Russell, Kaur Parwinder, Dudchenko Olga, Aiden Erez Lieberman, Yang Bicheng, Yang Huanming, Emery Aidan M, Webster Bonnie L, Brindley Paul J, Rollinson David, Chang Bill C H, Gasser Robin B, Young Neil D
Abstract excerpt
Urogenital schistosomiasis is caused by the blood fluke Schistosoma haematobium and is one of the most neglected tropical diseases worldwide, afflicting > 100 million people. It is characterised by granulomata, fibrosis and calcification in urogenital tissues, and can lead to increased susceptibility to HIV/AIDS and squamous cell carcinoma of the bladder. To complement available treatment programs and break the...
Topics
- Animals
- Chromosomes
- Genes, Protozoan
- Genetic Variation
- Genome
- Genome, Protozoan
- Genome-Wide Association Study
- Schistosoma haematobium
- Schistosomiasis haematobia