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The Genomic Architecture of Circulating Cytokine Levels Points to Drug Targets for Immune-Related Diseases

2024-04-22

Abstract excerpt

Circulating cytokines orchestrate immune reactions and are promising drug targets for immune-mediated and inflammatory diseases. Exploring the genetic architecture of circulating cytokine levels could yield key insights into causal mediators of human disease. Here, we performed genome-wide association studies (GWAS) for 40 circulating cytokines in meta-analyses of 74,783 individuals. We detected 359 significant as...

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Literature Corpus work
b2bb3993-10a2-551d-9a96-afdd1c8e0ad5
DOI
10.1101/2024.04.19.24306036
Open publication

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The Genomic Architecture of Circulating Cytokine Levels Points to Drug Targets for Immune-Related DiseasesDOI 10.1101/2024.04.19.24306036
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