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Article

Genetic study of circulating cytokines offers insight into the determinants, cascades and effects of systemic inflammation

2020-10-31

Abstract excerpt

Cytokines are the signalling molecules that underlie inflammatory processes. Here, we performed genome-wide association study (GWAS) analyses of 47 circulating cytokines in up to 13,365 individuals to identify protein quantitative trait loci (pQTL). Applying a novel approach, we incorporated pQTL and expression quantitative trait loci (eQTL) data of 10,361 tissue samples in 635 individuals to identify biologically...

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Literature Corpus work
5de70a1d-d639-550f-b841-59caa3cabc18
DOI
10.1101/2020.10.26.20219477
Open publication

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Genetic study of circulating cytokines offers insight into the determinants, cascades and effects of systemic inflammationDOI 10.1101/2020.10.26.20219477
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