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Cancer-associated fibroblasts reveal aberrant DNA methylation across different types of cancer

2024-02-07

Abstract excerpt

<h4>Summary</h4> Cancer-associated fibroblasts (CAFs) are critical components of the tumor microenvironment. Several studies demonstrated molecular differences between CAFs and normal tissue-associated fibroblasts (NAFs). In this study, we isolated CAFs and NAFs from liver tumors and analyzed their DNA methylation profiles. A subset of the CAFs exhibited aberrant DNA methylation, which was also reflected on gene...

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Literature Corpus work
b29fd2b6-b30b-59b9-9f7c-c2cdb8ab1824
DOI
10.1101/2024.02.02.578626
Open publication

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Cancer-associated fibroblasts reveal aberrant DNA methylation across different types of cancerDOI 10.1101/2024.02.02.578626
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