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Article

Aberrant transcriptional regulations in cancers: genome, transcriptome and epigenome analysis of lung adenocarcinoma cell lines.

Nucleic acids research - 16 Dec 2014

Suzuki Ayako, Makinoshima Hideki, Wakaguri Hiroyuki, Esumi Hiroyasu, Sugano Sumio, Kohno Takashi, Tsuchihara Katsuya, Suzuki Yutaka

Abstract excerpt

Here we conducted an integrative multi-omics analysis to understand how cancers harbor various types of aberrations at the genomic, epigenomic and transcriptional levels. In order to elucidate biological relevance of the aberrations and their mutual relations, we performed whole-genome sequencing, RNA-Seq, bisulfite sequencing and ChIP-Seq of 26 lung adenocarcinoma cell lines. The collected multi-omics data...

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Share to Adenocarcinoma
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 25378332
DOI: 10.1093/nar/gku885
PMCID: PMC4267666

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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