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Article

Epigenetic Regulation of Gene Expression in Cancer: Techniques, Resources, and Analysis

2017-03-08

Abstract excerpt

<h4>ABSTRACT</h4> Cancer is a complex disease, driven by aberrant activity in numerous signaling pathways in even individual malignant cells. Epigenetic changes are critical mediators of these functional changes that drive and maintain the malignant phenotype. Changes in DNA methylation, histone acetylation and methylation, non-coding RNAs, post-translational modifications are all epigenetic drivers in cancer, in...

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Identifiers and source

Literature Corpus work
ed52ceb1-832f-59bd-a6f5-3a465e167558
DOI
10.1101/114025
Open publication

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