Article
Distinct chromatin signatures of DNA hypomethylation in aging and cancer
2017-12-05
Abstract excerpt
<h4>Background</h4> Cancer is an aging-associated disease but the underlying molecular links between these processes are still largely unknown. Gene promoters that become hypermethylated in aging and cancer share a common chromatin signature in ES cells. In addition, there is also global DNA hypomethylation in both processes. However, any similarities of the regions where this loss of DNA methylation occurs is cu...
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Identifiers and source
- Literature Corpus work
- 505179d6-9e97-5626-bf59-aee1e96258d8
- DOI
- 10.1101/229476