Article

HNRNPA2B1 controls an unfolded protein response-related prognostic gene signature in prostate cancer

2022-06-23

Abstract excerpt

HNRNPA2B1 is associated with prostate cancer (PC) disease aggressiveness and underlies pro-tumourigenic cellular stress responses. By analysing >500 PC transcriptomes, we reveal that HNRNPA2B1 over-expression is associated with poor patient prognosis and stress response pathways. These include the “protein processing in the endoplasmic reticulum” (ER) pathway, which incorporates the unfolded protein response (UP...

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Literature Corpus work: b258a9bf-cde6-55a4-89d4-32af04abed63
DOI: 10.1101/2022.06.21.495112

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