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Article

Prognostic Significance of PPFIA2 in Localized Prostate Cancer: Integrative Analysis and Functional Validation.

Anticancer research - 1 Feb 2026

Liu Jipu, Hsu Cheng Ya, Lu Jianming, Zhang L E, Zhong Yuwei, Zhong Weide

Abstract excerpt

BACKGROUND/AIM: Prostate cancer (PCa) is a leading malignancy in men, with biochemical recurrence (BCR) indicating potential disease progression in up to 50% of patient's post-curative therapy. The liprin-α family gene PPFIA2 has emerged as a potential biomarker in PCa, yet its prognostic role in localized disease remains underexplored. MATERIALS AND METHODS: PPFIA2 expression was analyzed using high throughput...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 41617436
DOI: 10.21873/anticanres.17985

Genes

PPFIA2
BCR
CCK
SPOP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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