Article

MIXTURE: an improved algorithm for immune tumor microenvironment estimation based on gene expression data

2019-08-07

Abstract excerpt

RNA sequencing has proved to be an efficient high-throughput technique to robustly characterize the presence and quantity of RNA in tumor biopsies at a given time. Importantly, it can be used to computationally estimate the composition of the tumor immune infiltrate and to infer the immunological phenotypes of those cells. Given the significant impact of anti-cancer immunotherapies and the role of the associated i...

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Literature Corpus work: b1e8acbe-9a95-5589-94e0-55cdd26e477d
DOI: 10.1101/726562

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