Article

<i>Infino</i> : a Bayesian hierarchical model improves estimates of immune infiltration into tumor microenvironment

2017-11-21

Abstract excerpt

Robust quantification of immune cell infiltration into the tumor microenvironment may shed light on why only a small proportion of patients benefit from checkpoint therapy. The immune cells surrounding a tumor have been suggested to mediate an effective response to immunotherapy. However, traditional measurement of immune cell content around a tumor by immunohistochemistry, flow cytometry, or mass cytometry allows...

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Literature Corpus work: e4b468fd-58b7-519d-a9ce-0b93f2eb428c
DOI: 10.1101/221671

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