Article

GEM-DeCan: Improved tumor immune microenvironment profiling through novel gene expression and DNA methylation signatures predicts immunotherapy response

2021-04-11

Abstract excerpt

Quantifying the proportion of the different cell types present in tumor biopsies remains a priority in cancer research. So far, a number of deconvolution methods have emerged for estimating cell composition using reference signatures, either based on gene expression or on DNA methylation from purified cells. These two deconvolution approaches could be complementary to each other, leading to even more performant si...

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Literature Corpus work: a97a983a-77c4-59b7-ae84-99ddea38a7ba
DOI: 10.1101/2021.04.09.439207

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