Article

MAPK15 PROTECTS AGAINST THE DEVELOPMENT OF METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE

2024-12-23

Abstract excerpt

Accumulation of lipids in the liver characterizes metabolic dysfunction-associated steatotic liver disease (MASLD), the most prevalent chronic liver disease worldwide. As liver injury progresses to metabolic dysfunction-associated steatohepatitis (MASH), MASLD can predispose individuals to cirrhosis and hepatocellular carcinoma. Here, we characterized the first knockout mouse model for mitogen-activated protein ki...

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Literature Corpus work: b1a83260-28aa-588b-aa5e-029d703b599a
DOI: 10.1101/2024.12.23.630083

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