Article

Neutral Sphingomyelinase 2 Inhibition Limits Hepatic Steato-sis and Inflammation

2023-10-05

Abstract excerpt

<h4>Background: </h4> Non-alcoholic fatty liver disease (NAFLD) is manifested by hepatic steatosis, insulin resistance, hepatocyte death, and systemic inflammation. Obesity induces steatosis and chronic inflammation in the liver. However, the precise mechanism underlying hepatic steatosis in the setting of obesity remains unclear. Here we report studies that address this question. <h4>Methods:</h4> 14 weeks on hig...

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Literature Corpus work: 3bcc21b9-bb6d-5c82-9c19-c64e2766f1b7
DOI: 10.20944/preprints202310.0273.v1

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