Article

Mark4 ablation attenuates the pathological phenotype in tauopathy model mice

2023-10-05

Abstract excerpt

<title>Abstract</title> <p><italic>Background</italic> Accumulation of abnormally phosphorylated tau proteins is linked to various neurodegenerative diseases, including Alzheimer’s disease and frontotemporal dementia. However, what modifications of tau proteins cause disease phenotypes have not been fully understood. Microtubule affinity-regulating kinase 4 (MARK4) has been genetically and pathologically associat...

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Literature Corpus work: b18ebe57-c0a2-52f4-a637-d3d909c4419a
DOI: 10.21203/rs.3.rs-3382904/v1

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