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A nucleosome switch primes Hepatitis B Virus infection

2023-03-04

Abstract excerpt

<h4>Summary</h4> Chronic hepatitis B virus (HBV) infection is an incurable global health threat responsible for causing liver disease and hepatocellular carcinoma. During the genesis of infection, HBV establishes an independent minichromosome consisting of the viral covalently closed circular DNA (cccDNA) genome and host histones. The viral X gene must be expressed immediately upon infection to induce degradation...

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Literature Corpus work
b1899712-d1ba-5a26-842f-1cb88c5ced04
DOI
10.1101/2023.03.03.531011
Open publication

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A nucleosome switch primes Hepatitis B Virus infectionDOI 10.1101/2023.03.03.531011
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