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Article

Mapping the Interactions of HBV cccDNA with Host Factors

1 Sept 2019

Abstract excerpt

Hepatitis B virus (HBV) infection is a major health problem affecting about 300 million people globally. Although successful administration of a prophylactic vaccine has reduced new infections, a cure for chronic hepatitis B (CHB) is still unavailable. Current anti-HBV therapies slow down disease progression but are not curative as they cannot eliminate or permanently silence HBV covalently closed circular DNA...

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PMID: 31480501
DOI: 10.3390/ijms20174276

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