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Article

The Epigenetic Control of Hepatitis B Virus Modulates the Outcome of Infection

6 Jan 2016

Abstract excerpt

Epigenetic modifications are stable alterations in gene expression that do not involve mutations of the genetic sequence itself. It has become increasingly clear that epigenetic factors contribute to the outcome of chronic hepatitis B virus (HBV) infection by affecting cellular and virion gene expression, viral replication and the development of hepatocellular carcinoma. HBV persists in the nucleus of infected...

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PMID: 26779147
DOI: 10.3389/fmicb.2015.01491

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