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Epigenetic regulation and its therapeutic potential in hepatitis B virus covalently closed circular DNA

3 Feb 2024

Abstract excerpt

Human hepatitis B virus (HBV) infection is the major cause of acute and chronic hepatitis B, liver cirrhosis, and hepatocellular carcinoma. Although the application of prophylactic vaccination programs has successfully prevented the trend of increasing HBV infection prevalence, the number of HBV-infected people remains very high. Approved therapeutic management efficiently suppresses viral replication; however,...

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PMID: 39534573
DOI: 10.1016/j.gendis.2024.101215

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