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Article

Epigenetic modulation in chronic hepatitis B virus infection

17 Mar 2020

Abstract excerpt

The human hepatitis B virus (HBV) is a small-enveloped DNA virus causing acute and chronic hepatitis. Despite the existence of an effective prophylactic vaccine and the strong capacity of approved antiviral drugs to suppress viral replication, chronic HBV infection (CHB) continues to be a major health burden worldwide. Both the inability of the immune system to resolve CHB and the unique replication strategy...

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PMID: 32185454
DOI: 10.1007/s00281-020-00780-6

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