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The CCCTC-binding factor CTCF represses hepatitis B virus Enhancer I and regulates viral transcription

2020-05-09

Abstract excerpt

<h4>ABSTRACT</h4> Hepatitis B virus (HBV) infection is of global importance with over 2 billion people exposed to the virus during their lifetime and at risk of progressive liver disease, cirrhosis and hepatocellular carcinoma. HBV is a member of the hepadnaviridae family that replicates via episomal copies of a covalently closed circular DNA (cccDNA) genome. The chromatinization of this small viral genome, with...

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Literature Corpus work
275f4be9-4e3f-5f0f-b59c-7dcfcead43df
DOI
10.1101/2020.05.08.085548
Open publication

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The CCCTC-binding factor CTCF represses hepatitis B virus Enhancer I and regulates viral transcriptionDOI 10.1101/2020.05.08.085548
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