Article

Combined SNPs sequencing and allele specific proteomics capture reveal functional causality underpinning the 2p25 prostate cancer susceptibility locus

2024-04-04

Abstract excerpt

<title>Abstract</title> <p>Genome wide association studies (GWASs) have identified numerous risk loci associated with prostate cancer, yet unraveling their functional significance remains elusive. Leveraging our high-throughput SNPs-seq method, we pinpointed rs4519489 within the multi-ancestry GWAS-discovered 2p25 locus as a potential functional SNP due to its significant allelic differences in protein binding. H...

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Literature Corpus work: b13dff0c-6aef-5d9d-9282-8cc1773c9750
DOI: 10.21203/rs.3.rs-3943095/v1

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