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Article

Genetic and functional analyses implicate the NUDT11, HNF1B, and SLC22A3 genes in prostate cancer pathogenesis.

Proceedings of the National Academy of Sciences of the United States of America - 10 Jul 2012

Grisanzio Chiara, Werner Lillian, Takeda David, Awoyemi Bisola C, Pomerantz Mark M, Yamada Hiroki, Sooriakumaran Prasanna, Robinson Brian D, Leung Robert, Schinzel Anna C, Mills Ian, Ross-Adams Helen, Neal David E, Kido Masahito, Yamamoto Toshihiro, Petrozziello Gillian, Stack Edward C, Lis Rosina, Kantoff Philip W, Loda Massimo, Sartor Oliver, Egawa Shin, Tewari Ashutosh K, Hahn William C, Freedman Matthew L

Abstract excerpt

One of the central goals of human genetics is to discover the genes and pathways driving human traits. To date, most of the common risk alleles discovered through genome-wide association studies (GWAS) map to nonprotein-coding regions. Because of our relatively poorer understanding of this part of the genome, the functional consequences of trait-associated variants pose a considerable challenge. To identify the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22730461
DOI: 10.1073/pnas.1200853109
PMCID: PMC3396469

Genes

NUDT11
MSMB
NCOA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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Genetic and functional analyses implicate the NUDT11, HNF1B, and SLC22A3 genes in prostate cancer pathogenesis.PMID 22730461Read ↗

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