Article

Mild Chronic Kidney Disease Associated with Low Bone Formation and Decrease in Phosphate Transporters and Signaling Pathways Gene Expression

2023-02-13

Abstract excerpt

<h4>Background: </h4> Initial phases of molecular and cellular maladaptive bone response at early CKD remain mostly unknown. <h4>Methods:</h4> We induced mild CKD in SHRs by either arterial hypertension lasting six months (sham-operated rats, SO6) or in its’ combination with 3/4 nephrectomy lasting two and six months (Nx2 and Nx6, correspondently). Sham operated SHRs (SO2) and Wistar Kyoto rats (WKY2) with t...

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Literature Corpus work: b11ed798-d8b3-5fc9-94cb-238970843227
DOI: 10.20944/preprints202302.0207.v1

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