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Article

High calcium, phosphate and calcitriol supplementation leads to an osteocyte-like phenotype in calcified vessels and bone mineralisation defect in uremic rats.

Journal of bone and mineral metabolism - 1 Mar 2019

Bisson Sarah-Kim, Ung Roth-Visal, Picard Sylvain, Valade Danika, Agharazii Mohsen, Larivière Richard, Mac-Way Fabrice

Abstract excerpt

A link between vascular calcification and bone anomalies has been suggested in chronic kidney disease (CKD) patients with low bone turnover disease. We investigated the vascular expression of osteocyte markers in relation to bone microarchitecture and mineralization defects in a model of low bone turnover CKD rats with vascular calcification. CKD with vascular calcification was induced by 5/6 nephrectomy followed...

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Share to Bone Remodeling
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29603070
DOI: 10.1007/s00774-018-0919-y

Genes

DKK1
FGF23
DMP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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