Article

oFlowSeq: A multiplexed quantitative approach to identify genes affecting cell type enrichment using mosaic CRISPR-Cas9 edited cerebral organoids

2022-08-01

Abstract excerpt

Cerebral organoids are comprised of diverse cell types found in the developing human brain, and can be leveraged for the identification of critical cell types perturbed by genetic risk variants in common, neuropsychiatric disorders. There is great interest in developing high-throughput, multiplexed technologies to associate genetic variants with cell types. Here, we describe a multiplexed, quantitative approach (o...

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Literature Corpus work: b0fd0904-c93c-5b52-bbf7-83388cccf5fe
DOI: 10.21203/rs.3.rs-1825493/v1

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