Article

Transcriptome Analysis of Human Induced Excitatory Neurons Supports a Strong Effect of Clozapine on Cholesterol Biosynthesis

2020-08-06

Abstract excerpt

Antipsychotics are known to modulate dopamine and other neurotransmitters which is often thought to be the mechanism underlying their therapeutic effects. Nevertheless, other less studied consequences of antipsychotics on neuronal function may contribute to their efficacy. Revealing the complete picture behind their action is of paramount importance for precision medicine and accurate drug selection. Progress in c...

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Literature Corpus work: b0e592e0-79d9-5fcd-a618-ffb3393fbe55
DOI: 10.1101/2020.08.05.238212

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