Article

CPT2-Linked Fatty Acid Oxidation and Autophagy Nodes Connect NMN-Responsive Transcriptional Programs to Schizophrenia Biology

2026-08-05

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> Schizophrenia is a highly heritable psychiatric disorder with substantial clinical heterogeneity, and treatment-resistant schizophrenia remains difficult to define biologically when clozapine exposure is used as a proxy. Nicotinamide mononucleotide, an NAD⁺ precursor, has been shown to mitigate age-associated physiological decline in mice, and a recent re-anal...

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Literature Corpus work: d182f074-1212-5215-9d5a-d1f916c18746
DOI: 10.21203/rs.3.rs-10174269/v1

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