Article

iPSC-derived neurons as a tool for probing molecular pharmacology of antipsychotic action

2018-04-25

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Induced pluripotent stem cell derived neurons (iPSC-Neurons) provide a potential way to investigate molecular mechanisms of psychotropic drug action in human neurons. Until now such studies have relied on animal models or artificial expression systems in transfected cells. <h4>Methods</h4> Induced pluripotent stem cells were subjected to a dual SMAD inhibition differentiati...

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Literature Corpus work: c3a22516-dd63-5b82-a62e-d6a86caae374
DOI: 10.1101/308486

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