Article

Genotype-based “virtual” metabolomics in a clinical biobank identifies novel metabolite-disease associations

2023-10-11

Abstract excerpt

<title>Abstract</title> <p>Circulating metabolites act as biomarkers of dysregulated metabolism, and may inform disease pathophysiology. A portion of the inter-individual variability in circulating metabolites is influenced by common genetic variation. We evaluated whether a genetics-based “virtual” metabolomics approach can identify novel metabolite-disease associations. We examined the association between polyg...

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Literature Corpus work: b0e254aa-2244-5023-8565-87d7c0c27595
DOI: 10.21203/rs.3.rs-3222588/v2

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