Article

Genome-wide characterization of circulating metabolic biomarkers reveals substantial pleiotropy and novel disease pathways

2022-10-24

Abstract excerpt

<h4>ABSTRACT</h4> Genome-wide association analyses using high-throughput metabolomics platforms have led to novel insights into the biology of human metabolism 1–7 . This detailed knowledge of the genetic determinants of systemic metabolism has been pivotal for uncovering how genetic pathways influence biological mechanisms and complex diseases 8–11 . Here we present a genome-wide association study of 233 circulat...

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Literature Corpus work: 864d967f-1605-523b-9291-e2b310727b66
DOI: 10.1101/2022.10.20.22281089

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